ハヤカワ トオル   Hayakawa Toru
  早川 徹
   所属   鶴見大学・鶴見大学短期大学部 学長・副学長  学長・副学長 副学長
   職種   副学長
論文種別 【査読あり】 研究論文(学術雑誌)
言語種別 英語
査読の有無 査読あり
表題 Influence of mucin pre-adsorption for lipoteichoic acid adsorption on titanium surfaces.
掲載誌名 正式名:Dental materials journal
略  称:Dent Mater J
ISSNコード:18811361/02874547
掲載区分国内
巻・号・頁 39(6),pp.1039-1043
著者・共著者 Yoshida Eiji, Hayakawa Tohru
発行年月 2020/07
概要 We investigated the adsorption of lipoteichoic acid (LTA) on titanium surfaces by using the quartz crystal microbalance (QCM) method, and confirmed the influence of mucin (MUC) pre-adsorption on LTA adsorption. Two injection methods were evaluated. Namely, Method A: single-step injection of LTA solution to the Ti sensor, and Method B: MUC solution was injected to the Ti sensor followed by LTA injection on the MUC pre-adsorbed surface. QCM measurement revealed that the adsorbed amount of LTA by Method A was low and constant regardless of the increase in LTA concentration. In contrast, the adsorption amount of LTA in Method B increased according with increasing concentration of LTA and was significantly higher than that of Method A. The hydrophobic surface after MUC pre-adsorption was presumed to contribute to the enhancement of LTA adsorption. Our results revealed that MUC pre-adsorption to Ti is necessary for LTA adsorption in living tissue.
DOI 10.4012/dmj.2019-209
PMID 32624550