マツモト ナオユキ   Matsumoto Naoyuki
  松本 直行
   所属   鶴見大学  歯学部 歯学科 病理学
   職種   教授
論文種別 【査読あり】 研究論文(学術雑誌)
言語種別 英語
査読の有無 査読あり
表題 Extremely aggressive behavior of central giant cell granuloma after biopsy:a case report
掲載誌名 正式名:ORAL RADIOLOGY
ISSNコード:09116028
出版社 SPRINGER
巻・号・頁 31(2),pp.115-122
著者・共著者 Masao Araki,Teruhiko Ishii,Naoyuki Matsumoto,Kunihito Matsumoto,Kazuya Honda,Satoshi Nishimura,Takayoshi Tanaka
発行年月 2015/05
概要 Although central giant cell granulomas (CGCGs) appear to be benign, their radiographic findings are active. These tumors become severely invasive with the stimulus of surgery, resembling malignant tumors. Achieving the correct diagnosis is reportedly difficult because CGCGs are very similar to odontogenic jaw tumors. We herein describe an intriguing case of a 21-year-old male patient who was referred to our outpatient clinic with persistent swelling of the left buccal region. After making a provisional diagnosis of ameloblastoma from panoramic and computed tomography images, a biopsy was performed. Nine days after this operation, the intraoral lesion started to enlarge, causing facial disfigurement. Soon afterward, this lesion was examined by computed tomography, magnetic resonance imaging, and by both bone and tumor scintigraphy. Segmental resection of the mandible was conducted in the hospital, and the histopathological appearance was consistent with CGCG. Although CGCG tends to be indolent, the present case suggests that the stimulus of surgery can trigger clinically invasive behavior more characteristic of malignancy. CGCG exhibits variable features, but with the stimulus of su
DOI 10.1007/s11282-014-0177-1