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ハヤカワ トオル
Hayakawa Toru
早川 徹 所属 鶴見大学・鶴見大学短期大学部 学長・副学長 学長・副学長 副学長 職種 副学長 |
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| 論文種別 | 【査読あり】 研究論文（学術雑誌） |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Hydroxyapatite coating for titanium fibre mesh scaffold enhances osteoblast activity and bone tissue formation. |
| 掲載誌名 | 正式名：International journal of oral and maxillofacial surgery 略 称：Int J Oral Maxillofac Surg ISSNコード：13990020/09015027 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 41(10),pp.1304-1309 |
| 著者・共著者 | Hirota Makoto, Hayakawa Tohru, Yoshinari Masao, Ametani Akihiro, Shima Takaki, Monden Yuka, Ozawa Tomomichi, Sato Mitsunobu, Koyama Chika, Tamai Naoto, Iwai Toshinori, Tohnai Iwai |
| 発行年月 | 2012/10 |
| 概要 | This study investigated the bone regeneration properties of titanium fibre mesh as a tissue engineering material. A thin hydroxyapatite (HA) coating on the titanium fibre web was created using the developed molecular precursor method without losing the complex interior structure. HA-coated titanium fibre mesh showed apatite crystal formation in vitro in a human osteoblast culture. Titanium fibre mesh discs with or without a thin HA coating were implanted into rat cranial bone defects, and the animals were killed at 2 and 4 weeks. The in vivo experience revealed that the amount of newly formed bone was significantly higher in the HA-coated titanium fibre mesh than in the non-coated titanium fibre mesh 2 weeks after implantation. These results suggest that thin HA coating enhances osteoblast activity and bone regeneration in the titanium fibre mesh scaffold. Thin HA-coating improved the ability of titanium fibre mesh to act as a bone regeneration scaffold. |
| DOI | 10.1016/j.ijom.2011.12.035 |
| PMID | 22513355 |