ハヤカワ トオル   Hayakawa Toru
  早川 徹
   所属   鶴見大学・鶴見大学短期大学部 学長・副学長  学長・副学長 副学長
   職種   副学長
論文種別 【査読あり】 研究論文(学術雑誌)
言語種別 英語
査読の有無 査読あり
表題 Mold fabrication and biological assessment of porous DNA-chitosan complexes.
掲載誌名 正式名:Journal of biomedical materials research. Part B, Applied biomaterials
略  称:J Biomed Mater Res B Appl Biomater
ISSNコード:15524981/15524973
掲載区分国外
巻・号・頁 91B(2),pp.746-754
著者・共著者 Fukushima Tadao, Ohno Jun, Hayakawa Tohru, Kawaguchi Minoru, Inoue Yusuke, Takeda Shoji, Toyoda Mika, Okahata Yoshio
発行年月 2009/11
概要 A previous study revealed that DNA-chitosan complex prepared from the reaction between native DNA and chitosan in aqueous solution has suitable porosity for cell seeding, is nontoxic, and causes only a mild soft-tissue response. This simple and easy fabrication method for porous DNA-chitosan complex provides for a wide variety of applications as a scaffold material. The present study evaluated whether rinsing with PBS solution can fabricate DNA-chitosan complex in a mold and the histopathological responses of rat soft tissues to fabricated DNA-chitosan complexes.
DOI 10.1002/jbm.b.31451
PMID 19582845